Op 9 oktober vond de vierde editie van de Radboudumc Investment Day plaats. Wetenschappers, ondernemers en investeerders uit de life sciences & health-sector kwamen samen om kennis uit te wisselen, te netwerken en te praten over nieuwe samenwerkingen.
Het evenement werd gezamenlijk georganiseerd door Briskr, Oost NL, Radboudumc en de Radboud Universiteit. Met ruim 200 aanwezigen was de opkomst opnieuw groter dan het jaar ervoor.
Succesvolle matchmaking
Keynote spreker Floris Rutjes, hoogleraar Organische Synthese aan de Radboud Universiteit, trapte het programma van het evenement af. Hij vertelde over zijn persoonlijke ervaring en betrokkenheid bij verschillende start-ups, waaronder Chiralix, FutureChemistry en Synaffix. Zijn verhaal bleek een uitstekend voorbeeld te zijn van hoe het mogelijk is om een succesvolle academische carrière te combineren met ondernemerschap, door het inzetten van een ondernemende cultuur binnen je onderzoeksgroep.
Tijdens het hele programma gingen deelnemers gerichte 1-op-1 gesprekken aan, die vooraf en tijdens het evenement konden worden gepland via een matching tool. Anderen ontmoetten elkaar spontaan tijdens de pauzes, borrels en het diner na afloop. Een vruchtbare combinatie, aldus een van de aanwezige investeerders: Ik waardeer het format van de Investment Day enorm. Het stelt me in staat om relevante, diepgaande gesprekken te voeren in een ontspannen, informele sfeer. Dit soort kansen krijg je nergens anders in Nederland.
Nienke Timmermans wint Martijn Kriens posterprijs
Dit jaar was Nienke Timmermans de winnaar van de posterwedstrijd, met haar idee voor een algoritme dat tremoren bij patiënten met de ziekte van Parkinson monitort. Zij ontving de Martijn Kriens Best Poster Award: een aanmoedigingsprijs van 2.500 euro voor haar idee. Inzendingen in de posterwedstrijd werden niet alleen beoordeeld op hun wetenschappelijke verdiensten, maar ook op hun potentieel om uiteindelijk uit te groeien tot een succesvol product.
De prijs is vernoemd naar Martijn Kriens, die helaas eerder dit jaar is overleden. Martijn was, naast vele andere dingen, een van de grondleggers van en een belangrijke drijvende kracht achter de Investment Day. Zijn passie, energie en gezelschap worden dierbaar herinnerd door het organisatieteam van de Investment Day en iedereen die hem kende.
De volgende editie van de Investment Day zal plaats vinden op 8 oktober 2025. Bezoek de website voor meer informatie.
We’re organizing the 3rd Meeting Your Peers Engineers lunch event on Thursday November 28 at Noviotech Campus. Engineers from semiconductor companies in the region are welcome to join.
This time, ITEC will share more about their company, including Green laser technology for sustainable chip assembly and the eXtreme Assembly Lab. They are also sponsoring the lunch.
Joep Stokkermans, R&D Director ITEC ITEC – “Redefining Semiconductor Manufacturing” Headquartered in Nijmegen, the Netherlands, ITEC is a back-end semiconductor equipment manufacturer, specialized in high-volume production of semiconductors. ITEC is rooted in semiconductor manufacturing, combining over 30 years of state-of-the-art equipment and automation expertise as partner to Philips, NXP and Nexperia. In July 2021, ITEC became a separate legal entity to be able to address external markets and customers.
ITEC solutions With an installed base of more than 2600 of the industry’s most advanced tools, ITEC is committed to embed the latest technologies and process expertise into tailored solutions that redefine manufacturing. ITEC enables its customers to excel in quality, productivity, and sustainability with the lowest total cost of ownership.
Jasper Wesselingh, Mechatronic Architect ITEC Green laser technology for sustainable chip assembly The chip assembly roadmap for high-volume production is largely determined by smaller chip sizes and reduced energy consumption per assembled chip. This talk will discuss how a shift from mechanical to laser based processes can enable this roadmap. We dive into the laser-assisted processes and show the steps from lab-scale experiments to prototype equipment.
Dr. Ir. Marcel Tichem, TU Delft Associate Professor TU Delft, Department of Precision and Microsystems Engineering Scientific program leader X.AL
X.AL – eXtreme Assembly Lab Future chip assembly processes need to comply with challenging demands: achieving 10x higher throughput, handling die sizes well below 100µm, and reducing the environmental footprint. X.AL is a joint research programme of TU Delft and ITEC for establishing the technological foundation to meet these demands. Future assembly processes will be based on non- & soft-contact force fields to replace mechanical and contact-based chip assembly.
Program:
12:00 – 12:30 Walk in & Lunch
12:30 – 12:40 Presentation ITEC (Joep Stokkermans, R&D Director ITEC)
12:40 – 13:40 In-depth presentations:
Green laser technology for sustainable chip assembly (Jasper Wesselingh, Mechatronic Architect ITEC)
Don’t miss this opportunity to network and expand your knowledge! Sign up quickly and reserve your spot on Nov 28. It will be an inspiring and valuable session that you won’t want to miss!
Tech Tour together with Bochum Wirtschaftsentwicklung is hosting the first edition of the AI for Health programme. Artificial intelligence (AI) and related technologies are playing an increasingly important role in the healthcare industry, having the potential to transform many aspects of patient care, prevention and discovery processes. The programme of TT AI for health covers the full spectrum of solutions which will drive innovation in these sectors.
When? 22-23 January 2025 Where? Bochum, Germany
SUB SECTORS
WHY JOIN THE PROGRAMME?
Attend Multiple pitching sessions, keynote speeches and panel discussions
Meet Leading investors and pioneering entrepreneurs in one place
Discover Exclusive insights into emerging trends and innovative solutions
Our world is facing many challenges, from climate change to the energy transition. But one crisis that often goes unnoticed is the alarming decline in biodiversity and soil health. HAL24K Agri, led by Bob Klein Lankhorst, is pioneering a unique approach to tackling these issues.
Soil health is at an all-time low. This has a direct impact on our food supply: crops are becoming less nutritious, and food security is declining. Farmers are finding that their soils are less resilient and retain less water. And all of this is threatening biodiversity.
HAL24K Agri is not only addressing these issues but is also offering a glimmer of hope. The company is developing new solutions for monitoring soil life and crops, collectively known as the ‘Soil Health Suite.’ These innovative solutions can potentially revolutionise the way we monitor and manage soil health.
Innovative measurement methods soil life
Bob studied environmental science and then started his own company, ‘Bodemliefde’ (meaning “for love of soil”). Here, he discovered that soil life plays an important role in soil health. However, Bob also realised that existing measurement methods needed to be more comprehensive. For example, you can measure the soil chemically/physically: what elements are present in the soil? And what is the pH value?
Then, there is the biological way of measuring: looking at the life of the soil. In practice, this is still done roughly. For example, some methods measure biomass. This looks at how many bacteria there are in the soil. This measurement is very crude: you get numbers but can’t tell which species are in the soil.
On the other hand, there are DNA methods. These methods give an insight into genetic codes, but it takes time and effort to quantify the codes. So, you have two methods of measurement, but you can’t use them together effectively. Bob saw a gap in the market. So, he started thinking: what would be a good way to look at the soil more thoroughly?
Learning by observing
“You have to observe”, stresses Bob. “You can learn a lot about soil life by looking at it. Soil life is small, so there is quickly a lot of life in a square metre of soil. That’s why I have been researching whether we can use AI to automate microscopes. This would allow us to quickly and accurately take photos or videos of the soil at the right magnification. You can categorise these images and efficiently analyse many soils by observation.”
“All because you want to know what is in your soil, how much there is, and what effect it has. It is a case of what you see is what you get. Soil life tells you a lot about soil health. By getting the right information from your soil, you can improve soil management. This way, we can improve soil function, keep soil healthy, retain more water, increase biodiversity, and provide the right nutrient value for plants.”
Measuring biodiversity
But how do you accurately measure biodiversity? Often, this is done by counting the number of trees or birds. But it takes more than just counting numbers. According to Bob, the exciting thing about soil life is that you can find an incredible amount of information in just one square metre of soil. That is why HAL24K Agri is developing special models for tiny creatures: nematodes, also known as roundworms.
Bob: “They are the most common animal species on Earth. Did you know that about 4 out of 5 animals are nematodes? That’s why nematodes are ideal to measure: they are very localised in the soil and have life cycles of a few weeks, months, or years. They are found in soils all around the world, including highly polluted or poor soils. If you can measure populations even in polluted soils, nematode populations can tell you something about the state of the soil. Healthy soils have more nematodes and other populations than unhealthy soils. So, the type and number of nematodes can tell you a lot about the quality of the soil. In addition, nematodes have been studied frequently and extensively by scientists. They are an excellent ecological indicator of soil conditions.”
Accessible measurements
The measurement process is designed to be user-friendly and accessible. Bob explains: “You take a soil sample and send it to our lab. It’s a quick process, especially when compared to other methods. Our hardware is portable, and the protocols are simple. Depending on your requirements you can even conduct it in a company van. The results are then available on our platform. It’s fascinating when you measure over time. That’s why I always recommend starting with a baseline measurement and then build a series. That way you can easily see the differences in soil health between fields. Later, after several measurements, you can start making predictions. The software is constantly improving and getting more accurate.”
The only way forward is together
Bob has seen a great deal of interest in HAL24K Agri’s innovative measurement system. The system is gaining traction among various stakeholders, including the agricultural sector, the scientific community, and large agri-food companies. Municipalities and governments are also showing interest, as they are keen to label soil quality. “Our technology is accessible and more meaningful than alternatives. All parties that are in any way soil-dependent can benefit from it.”
Bob has significantly benefited from Briskr and the Business Angel Network Nijmegen (BANN) on his way to healthier soils. “Briskr helped us with advice, network support and connections with relevant partners. This enabled us to grow faster”, says Bob. “BANN also provided access to funding and strategic advice from experienced investors, who share capital, expertise, and guidance. Good preparation for the BANN was therefore essential: with a clear pitch, a clear business plan and financial projections, we communicated our vision and ambitions well. The positive feedback and interaction with the investors is helping us to take concrete steps in our strategic growth and development”.
Aiming for a healthy global impact
HAL24K Agri’s long-term goal is clear: “We want to become the global standard for measuring functional biodiversity and ecosystem services so that we can make better decisions for our soils and human well-being on Earth. By understanding what is happening at a microscopic level, we can better align our actions with the natural world around us. By knowing all the flora and fauna and the negative impacts we regularly have on them, we can learn from them. Biodiversity recovery is hopeful: you can see how life forms respond to restoration or when they are given the space to thrive again. If we do it together, we can correct what we have damaged and make it better than ever!”
Only one week left until we see each other again at the 4th edition of the Radboudumc Investment Day. In the meantime, we’d like to give you a taste of what to expect from some of our esteemed speakers.
Bram van Ginneken
Bram van Ginneken (Professor of Medical Imaging Analysis and founder of Plain Medical) will talk about the rapidly growing demand for CT and MRI studies, and how that puts unsustainable pressure on radiologists. Plain Medical, a startup founded by an experienced team of medical image specialists and radiologists, has developed an AI engine that can compile radiology reports automatically. This can help radiologists report more efficiently and more accurately.
Thom Frielink
Tom Frielink (Associate at Curie Capital) will offer insights to entrepreneurs and scientists into how Venture Capital firms operate. He will explain the inner workings of these firms, and how this impacts decision making processes. If you’re an entrepreneur looking for investment, take advantage of these insights!
Marc Robillard
Marc Robillard (CEO Tagworks Pharma) will walk you through the premature spinout from Philips in 2011, the “40 days” traversing the desert, the key improvements of the click-to-release technology along the way, the crucial NL-based seed round in 2021, and how they arrived at the game changing 60 M Series A in 2023 with blue chip EU and US investors.
Practical information for October 9, 2024
Jointly organized by Radboudumc, Radboud University, Briskr and Oost NL, the Investment Day is a matchmaking event for investors, entrepreneurs and top researchers in the life sciences & health domain.
The event will take place at the Radboudumc Experience Center from 12.00h to 17.30, with optional dinner and networking afterwards. The previous editions led to several new investments for start-ups who visited the event, and lasting contacts!
To ensure a good balance between the three target audiences, the event is invite only. If you’re interested in participating, please send an email to Marion Schouten (marion.schouten@radboudumc.nl) to receive further information.
NXTGEN Hightech, Invest-NL Deep Tech Fonds, and Topsector Life Sciences & Health (Health~Holland) are delighted to invite you to our upcoming event focused on Lab-on-Chip, Organ-on-Chip, and biosensing technologies, taking place on Monday, November 4, 2024.
Event details:
Location: Villa Jongerius, Doctor M.A. Tellegenlaan, Utrecht
Time: Walk-in from 13:30h; the event will conclude with a networking session starting at 17:15h.
We are excited to begin the event with the presentation of the Invest-NL Deep Tech Fund Report. This report will provide a comprehensive market analysis of the lab-on-a-chip, organ-on-a-chip, and biosensing research landscape, with a focus on startups and funding opportunities in the Netherlands.
After the presentation of the report we will host multiple break-out sessions in which we discuss:
Collaborative strategies for market access
Commercializing Organ-on-Chip and Lab-on-Chip technologies
Investor attractiveness and funding opportunities at different stages
We will conclude our formal program with a panel discussion about scaling Dutch biotech innovation for the European market.
This event offers a unique opportunity to network with industry leaders, investors, and innovators. You are welcome to bring a colleague to join the discussions and expand your network.
We look forward to seeing you on November 4th in Utrecht! Sign up here.
This year we organise every month a walk-in for health and hightech companies.
Rienk works as intellectual property (IP) advisor for the Netherlands Patent Office and is eager to help start-ups and SMEs with their questions on IP-rights in the broadest sense of the word. The Netherlands Patent Office is an official Dutch government body whose main goal is to stimulate innovation in the Netherlands. It does so by providing support and guidance to business owners, the services sector, scientists, researchers, teachers, and students. You can consult with Rienk about any patent-related queries or other ways to protect your IP. The services provided are confidential, free-of-charge, and without commercial interest.
Contact Rienk Rienksma
You can just walk-in or make an appointment if you like:
Innovatieve bedrijven met internationale ambities en activiteiten krijgen beter toegang tot beschikbare mogelijkheden voor ondersteuning en investering. De regionale ontwikkelingsmaatschappijen (ROM’s) en Invest International hebben hiertoe een samenwerkingsovereenkomst ondertekend. De overeenkomst bevat ook afspraken over kennisdeling, mogelijkheden voor exportfinanciering en gezamenlijke handelsmissies.
De ROM’s staan als investeerder aan de wieg van het leeuwendeel aan innovatieve startups in Nederland. In 2023 investeerden de ROM’s (totale fondsvermogen € 2,3 miljard) vanuit hun eigen fondsen € 219 miljoen in 372 startups, scale-ups en innovatieve mkb’ers. Ruim 50% van de bedrijven die venture capital aantrekt, doet dit mede dankzij een investering vanuit een regionaal ontwikkelingsfonds. Als startups uitgroeien tot scale-ups doen ze dit vaak in een internationale context. Invest International kan in deze fase doorinvesteren en internationale groei mogelijk maken. Invest International heeft een eigen investeringskapitaal van 833 miljoen euro.
Mondiale uitdagingen
De afspraken tussen de ROM’s en Invest International richten zich op start- en scale ups die mondiale uitdagingen oplossen, zoals klimaatneutrale energieoplossingen, duurzame voeding en innovaties in de gezondheidszorg. Invest International en de ROM’s bekijken welke portfoliobedrijven van de regionale ontwikkelingsmaatschappijen in aanmerking komen voor een internationale vervolginvestering van Invest International. Omgekeerd verwijst Invest International bedrijven die voor hen in een te vroege fase zitten door naar de ROM in de regio van het betreffende bedrijf.
“Internationalisering is naast innovatie de pijler onder het huidige en toekomstige verdienvermogen van Nederland”, stelt Brigit van Dijk-van de Reijt, algemeen directeur van de Brabantse Ontwikkelings Maatschappij (BOM), namens ROM-Nederland. “De samenwerking van Invest International met de regionale ontwikkelingsmaatschappijen stelt ons nog beter in staat om missiegedreven startups, scale-ups en het mkb met internationaliseringsambities een vliegende start te geven en zo het Nederlands verdienvermogen in het buitenland te vergroten.”
“Een goede samenwerking tussen Invest International en regionale ontwikkelingsmaatschappijen is van cruciaal belang om Nederlandse bedrijven optimaal te kunnen ondersteunen bij hun internationale groei”, stelt Eelco Benink, Head of Equity van Invest International. “Waar de ROM’s in nauw contact staan met de bedrijven in hun regio specialiseert Invest International in financiering van internationale expansie en internationale handel. Samen versterken we de internationale positie, concurrentiekracht en het verdienvermogen van Nederlandse bedrijven, en dragen we bij aan een duurzame en vooruitstrevende economie.”
Voorinvesteringen
Naast de genoemde afspraken richt de overeenkomst zich ook op het delen van kennis tussen beide partijen (onder meer groene waterstof). Daarnaast wordt bekeken of Invest International exportfinancieringen kan verstrekken. Als bedrijven buitenlandse markten betreden vraagt dit om risicovolle voorinvesteringen. Verder zullen Invest International en de ROM’s de samenwerking op gezamenlijke handelsmissies intensiveren.
Dit artikel is geschreven door Oost NL en op de website te vinden via deze link.
Is jouw zorginnovatie getest en klaar voor de markt? Wil jij jouw markt verder uitbreiden of je innovatie zichtbaar maken? Doe dan mee aan deze tiende editie van de Nationale Zorginnovatieprijs! Meld je dan uiterlijk 31 oktober 2024 voor 12:00 uur aan voor deze jubileumeditie en maak kans op €10.000 om jouw innovatie door te ontwikkelen! Kijk voor de voorwaarden en aanmelden op www.zorginnovatie.nl/nationale-zorginnovatieprijs.
Who doesn’t know the feeling? The alarm goes off in the morning, but we’re still far too tired to get up. It sometimes feels as if our body lives according to a different clock. That’s possible, scientists say. There is actually a small group of nerves in the hypothalamus that acts as a ‘circadian clock’ and determines the daily rhythm of our lives. It not only regulates our sleep/wake rhythm but also influences our metabolism, hormone release, moods, and much more. Today’s 24/7 society causes desynchronization in this, which can have negative consequences for our health. Think of a higher risk of obesity, cardiovascular diseases, and diabetes.
In the BioClock project, a wide variety of researchers throughout the Netherlands are working together to unravel the secrets of the circadian clock. Andries Kalsbeek (Netherlands Institute for Neuroscience, Amsterdam UMC) is investigating how the bio-rhythm influences our hormone levels and how energetic we feel. Laura Kervezee (Leiden UMC) is working on new strategies to support the natural functioning of the circadian clock, such as for night workers, the elderly, or hospital patients. On Wednesday, October 16, at the Science Café, they will discuss (in Dutch) their latest findings on the workings of the circadian clock and the consequences of its disruptions. And Séance … they’ll play according to their own rhythm this evening; tune in!
scientists /8pm Andries Kalsbeek (Nederlands Herseninstituut) and Laura Kervezee (Leiden UMC)